Involvement of TAGE-RAGE System in the Pathogenesis of Diabetic Retinopathy

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Involvement of TAGE-RAGE System in the Pathogenesis of Diabetic Retinopathy

Diabetic complications are a leading cause of acquired blindness, end-stage renal failure, and accelerated atherosclerosis, which are associated with the disabilities and high mortality rates seen in diabetic patients. Continuous hyperglycemia is involved in the pathogenesis of diabetic micro- and macrovascular complications via various metabolic pathways, and numerous hyperglycemia-induced met...

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The RAGE axis in early diabetic retinopathy.

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ژورنال

عنوان ژورنال: Journal of Ophthalmology

سال: 2010

ISSN: 2090-004X,2090-0058

DOI: 10.1155/2010/170393